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Symbol
Name
ID

Gimap3
GTPase, IMAP family member 3
MGI:1932723

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal B cell proliferation

decreased B cell proliferation

intestinal inflammation

colitis

thymus atrophy

decreased thymocyte number

abnormal CD8-positive, alpha-beta T cell differentiation

increased neutrophil cell number

increased granulocyte number

abnormal lymphocyte cell number

decreased mature B cell number

decreased B-1 B cell number

decreased B cell number

decreased NK cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased NK T cell number

decreased T cell number

decreased lymphocyte cell number

abnormal leukocyte morphology

abnormal spleen morphology

spleen hypoplasia

abnormal spleen B cell follicle morphology

decreased spleen B cell follicle number

decreased spleen B cell follicle size

abnormal B cell physiology

decreased IgG1 level

decreased IgG2a level

decreased IgG2b level

decreased IgG3 level

decreased IgG level

decreased IgM level

abnormal NK T cell physiology

decreased circulating interferon-gamma level

decreased circulating interleukin-4 level

small lymph nodes

decreased interferon-gamma secretion

decreased interleukin-4 secretion

decreased tumor necrosis factor secretion

abnormal response to transplant

Availability

Mouse Genotype

Gimap3^tm1.1Yout/Gimap3^tm1.1Yout

Gimap5^m1Btlr/Gimap5^m1Btlr

Gimap5^tm1Wlr/Gimap5^tm1Wlr

Gimap5^tm1Yout/Gimap5^tm1Yout

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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